21Later, Isaac prayed to the LORD on behalf of his wife, because she was barren. And the LORD heard his prayer, and his wife Rebekah conceived.
22But the children inside her struggled with each other, and she said, “Why is this happening to me?” So Rebekah went to inquire of the LORD,
23and He declared to her:
“Two nations are in your womb,
and two peoples from within you will be separated;
one people will be stronger than the other,
and the older will serve the younger.”
24When her time came to give birth, there were indeed twins in her womb.
25The first one came out red, covered with hair like a fur coat; so they named him Esau.
26After this, his brother came out grasping Esau’s heel; so he was named Jacob. And Isaac was sixty years old when the twins were born.
— Genesis 25:21-26