28Regarding the gospel, they are enemies on your account; but regarding election, they are loved on account of the patriarchs.
29For God’s gifts and His call are irrevocable.
30Just as you who formerly disobeyed God have now received mercy through their disobedience,
31so they too have now disobeyed, in order that they too may now receive mercy through the mercy shown to you.
32For God has consigned everyone to disobedience so that He may have mercy on everyone.
— Romans 11:28-32

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Article by Max Lucado

What do we let define us, call or catastrophe? Max Lucado from his book "You'll Get Through This" encourages us to not let our disappointments define us but instead let God's destiny for us define us.